You might think I’m crazy for saying that a plant could mimic the effects of fasting without fasting… but it’s true.
And in just a few short minutes I’ll prove it to you – with cold hard evidence. The facts. The science. The undeniable proof.
And no, it’s not magic mushrooms.
This stuff is completely legal…
Now we’ve learned that it’s the key to unlocking your metabolism…
As well as protecting your cells from inflammation, insulin resistance, and prediabetes.
It can even balance blood sugar, no matter how many pancakes you eat for breakfast.
And banish the afternoon slump so you can sustain lasting energy and focus at work.
It’s so powerful, you’d think it came from a lab, created by a mad scientist. Instead, Mother Nature has given us this gift.
Before I reveal the name, let me show you exactly how it works.
Imagine a switch in every cell of your body.
Fat cells, muscle cells, skeletal cells… everything.
When it’s flipped on, your body does some pretty amazing things.
Things like releasing fat and reducing inflammation.
It also kickstarts autophagy. Autophagy is your body’s way to clean out damaged cells and replace them with new and healthy ones.
All the things we want.
Insulin resistance goes up.
And you get more oxidative stress.
There are three things you can do:
1. Prolonged fasting.
2. Significant calorie restriction.
3. Strenuous exercise.
Doesn’t sound all that appealing, does it?
Makes you feel like your only hope for achieving those goals would be to hop on the treadmill for 8 hours and just barely nibble on your food throughout the day like a little chipmunk.
AMPK is not a drug.
It’s an enzyme hidden within every cell of your body that acts as a master control switch for everything… from weight loss to aging.
And its job is to maintain body homeostasis between energy consumption (hunger) and energy production (desire to exercise).
And subconsciously, it controls a lot more of your daily activities than you realize.
However, solving the problem with AMPK isn’t always so simple, because AMPK can be influenced by so many factors.
Things like diet, exercise, sleep, stress, age, and even genetics.
What we do know, however, is that AMPK clearly declines with age – leaving you more susceptible to energy swings, weight gain, and brain fog as you get older.
Unintentionally, millions of people around the world have been getting the benefits of AMPK activation through fasting.
However, the more popular intermittent fasting isn’t as much of a potent activator as some might hope.
A study showed that it takes 24 hours of fasting to get the benefits of AMPK and autophagy.
Yet it seems nearly everyone is talking about intermittent fasting. Heck, 1 in 4 US adults said they tried it for fat loss.
Many studies have proven AMPK to be a powerful driver to increase lifespan, some by as much as 15% 
One of the major benefits of fasting is cell recycling — out with the old, in with the new. AMPK triggers autophagy which is known as one of the most potent drivers to look younger and slow aging at the cellular level.
One of the major benefits of fasting is cell recycling – out with the old, in with the new.
AMPK triggers autophagy which is known as one of the most potent drivers to look younger and slow aging at the cellular level.
Not only does AMPK stop glucose from being stored, it also blocks metabolic pathways that store and create fat cells [5, 6]
AMPK is mainly known to decrease inflammation by activating SIRT1 — which can epigenetically reprogram inflammation 
The World Anti-Doping Agency has actually banned substances known to boost AMPK for their performance-enhancing properties.
Exercise can promote insulin sensitivity and help you use carbs for energy, instead of storing them as fat.
But without AMPK, exercise won’t increase insulin sensitivity.
Because this enzyme ramps up the production of powerful antioxidants, like NFR2, it plays a critical role in fighting free radicals.
Many studies have proven AMPK as a powerful driver to increase lifespan, some by as much as 15%.
Glycation End Products (AGEs) cause elastin and collagen in skin to get hard and brittle. This in turn causes the skin to look aged and wrinkly. AMPK can stop this process by keeping glucose stable and avoiding AGEs altogether. 
Let’s say you sleep your 8-9 hours, eat super healthy, and get in some form of exercise nearly every day…
Stress is bad. Everyone knows that. But why?
When we’re stressed, our bodies turn up hormones that increase blood sugar… even when we don’t eat.
Stress from work. Stress from family. Stress from lack of sleep. Doesn’t matter where it comes from… it’s nearly impossible to avoid.
Stress makes our cells less responsive to insulin. And when that happens, our bodies have to produce more insulin.
And in the presence of insulin, AMPK is in handcuffs.
It can’t and won’t give you the same powerful anti-aging and fat loss benefits you want.
Poor diet, lack of exercise, and stress can cause a rise in blood glucose.
When blood glucose is elevated (anytime you eat or get stressed), insulin is released.
If this happens consistently, our cells become less responsive to insulin.
This blunts the effect of AMPK, the enzyme that keeps us young, healthy, and fit.
It’s harder to lose weight, avoid energy crashes, and fight against wrinkles.
Even skinny, fit, and otherwise healthy people still suffer from stress. They still struggle to stay asleep at night. Their job or kids might get on their nerves.
And then it begins to show – under their eyes, around their waist, or maybe through the thinning hairs on their head.
So it’s no surprise that The Journal of Clinical Endocrinology & Metabolism found that: “insulin resistance is not necessarily an essential component of Type 2 diabetes” 
Just because your test results aren’t out of range yet… don’t wait for them to be. Don’t wait for the underlying symptoms to pile up.
Like when a process called glycation happens – where your skin begins to wrinkle because the elevated glucose mixes with collagen in your skin cells.
So why wait?
Poor insulin sensitivity and glucose instability can affect you tomorrow when you wake up, causing mood swings, energy crashes, and sugar cravings.
So without boring you with all the scientific jargon, just know this:
The more insulin sensitive you are…
The less your body needs to use food for energy…
The more that AMPK switch can be turned on…
The easier it is to lose weight, look younger, and boost energy
Just know that there are tens of millions – if not hundreds of millions – of people experiencing the same issues in the US alone.
Most of them ignore it and it becomes their normal. They can’t even remember what “feeling good” really feels like.
That’s why you discover people later in life wishing they would have done something sooner.
So, like I said before, you have another option…
Want to see what’s behind door number two?
As you might already assume, a lot of people would love to experience the benefits of fasting, without the risks of a drug made in a lab.
So there has been a lot of talk around this natural alternative…
A substance extracted from a plant called goldenseal, which grows in the eastern United States.
Maybe you’ve heard of it, maybe you haven’t.
But its effects on blood sugar, insulin, and even AMPK can be compared to the pharmaceutical alternatives… without pharmaceutical side effects.
It’s been used for decades in Chinese and Ayurvedic medicine with proof of effectiveness and safety, so you don’t need a prescription or doctor visit.
That’s why its prevalence in weight loss and glucose support supplements has skyrocketed in recent years.
However, it does have some flaws.
The main one is its poor bioavailability. The body simply can’t utilize all the benefits present in its traditional form.
That’s why scientists set out to increase bioavailability, and a new scientific discovery isolated the active compound in berberine.
It’s called Dihydroberberine (or DHB for short), and it’s a derivative of berberine that’s more bioavailable.
The tough part is getting your hands on it, since it’s patented. But we didn’t stop there…
He’s an expert in Molecular Pharmacology and Physiology and a Research Scientist at the Institute for Human and Machine Cognition.
When Dr. Dom isn’t developing new metabolic-based strategies to combat everything from epilepsy to neurodegenerative diseases to cancer, he’s also an Associate Professor at the University of South Florida Morsani College of Medicine.
And the formula that we created was…
The secret of berberine is DHB. While berberine has become a very popular product for weight loss and glucose control, DHB has been shown to be 5 times more powerful.
Glucovantage® DHB has been shown to:
Improve insulin sensitivity via AMPK activation.
Support healthy blood glucose and insulin levels
Support reducing glycation correlated with aging
Improve body composition and nutrient partitioning
Glycostat® supports insulin sensitivity and insulin-like actions to help keep glucose levels stable throughout the day.
With Glycostat® you can avoid the spikes and dips in your energy and insulin.
Cinnamon has been well-studied to support healthy blood sugar, blood pressure, and mental performance. One study showed a 20-fold improvement in glucose metabolism. 
However, unlike typical cinnamon, Cinnulin PF® is a water-soluble extract using Controlled Polymer Purification Technology. With this process, it isolates and potentiates the active ingredients, while avoiding the potential toxins from whole cinnamon.
Cinnulin PF® has been clinically shown to:
Support normal blood sugar levels
Promote healthy body composition
Promote healthy blood pressure
And support women’s hormone balance.
Innoslim® is a stimulant-free ingredient patented and developed to support healthy weight and glucose metabolism.
One of the major reasons it works so well compared to other stimulant fat burners is its powerful effects on AMPK.
InnoSlim® goes to work for you inside the body to nourish the cells with abundant nutrients to foster a healthy metabolic environment – and most of all to rid yourself of any unwanted fat.
Here are the research-backed benefits of Innoslim®:
Reduce glucose absorption by 46%
Increase AMPK by 23%
Increased ACC by 100% – a powerful mediator for weight.
Expect to experience less hunger, a change in weight, and steady energy levels when using Innoslim®
Banaba Leaf Extract
G. Sylvestre Extract
Tibetan Holy Fruit
Blood Sugar Breakthrough includes ingredients specifically chosen to balance blood glucose, improve insulin sensitivity, and increase AMPK activation including:
Tibetan Holy Fruit Extract 300:1
Banaba Leaf Extract
Gymnema Sylvestre leaf Extract
How much would you pay to get the anti-aging and fat loss benefits of fasting 365 days of the year without having to fast?
How much easier would it be to lose weight if you didn’t have to fight hunger pangs, sugar cravings, and energy swings?
How much more productive would you be if you didn’t have a post-meal slump, 2:30 “need a nap” feeling, or brain fog?
Does not cause the same GI distress that other solutions might.
Does not inhibit the benefits of exercise or a healthy diet. (And as a 3-time All-Natural bodybuilding champion, it’s something I can stand behind.)
100% natural, with no synthetic additives, preservatives, or chemicals.
No prescription required, so anyone can experience the power of our 13 research-backed ingredients
But now you, from the comfort of your home, can get the same powerful anti-aging and weight loss benefits while helping stabilize your blood sugar levels and manage your carb intake.
Plus, if you’re like me, I’m looking for every edge I can get. Especially as I get older.
When I saw not just one, but four, patented and clinically backed ingredients, the first thought that ran through my mind was… this is gonna cost a fortune.
And with nine other powerful ingredients that have been used around the world for centuries, I worried whether this product would be affordable for anyone.
Luckily I was wrong.
365-Day Money Back Guarantee
365-Day Money Back Guarantee
365-Day Money Back Guarantee
We understand you might be skeptical. But you’ve seen the research. We’ve packed the absolute, most powerful, clinically studied ingredients into one capsule and have made it available without breaking the bank.
Plus, our company — BiOptimizers — has been in business for 16 full years. We stand behind our products and guarantee that they will do what we say they do.
And to make sure you have plenty of time to give our product a fair shot and make your decision, we’re giving you 365 days to decide.
In the highly unlikely event you’re not blown away, we refuse to keep even a penny of your money.
If you are not completely satisfied with your BiOptimizers product for any reason between today and 365 days from now, just send back your remaining unopened bottles of the product and we'll give you a full refund (minus the cost of shipping and handling). If you open a second bottle, you no longer qualify for any guarantee. Reach out to our customer happiness team and they will take complete care of it.
If you want to maximize the benefits of Blood Sugar Breakthrough we suggest you take it with meals (especially your big meals) to blunt the insulin response.
That way, you won’t experience the post-meal fatigue or dips in energy later.
Also, if you happen to intermittent fast and would like to get in a fasted state quicker, take Blood Sugar Breakthrough 1-2 hours before bedtime.
With lower insulin levels and balanced blood sugar at night, you’ll experience more restful uninterrupted sleep.
This is why we worked so hard, researching the purest, most potent source of Berberine and other clinically studied ingredients and made it available to you, at the best possible price.
Save and get started with Blood Sugar Breakthrough using any button on this page.
Your energy, metabolism, body fat, skin…
Indeed EVERY cell in your body… will thank you for it.
President and Co-Founder of BiOptimizers
Advisor to the American Anti-Cancer Institute
Author of the Best Selling Book 'Staying Alive In A Toxic World'
3-Time All Natural National Bodybuilding Champion
P.S. If you’re still not convinced of the power of Blood Sugar Breakthrough, just look at all of these studies (links below) — it’s everything we’ve referenced in this letter and more…
 Salminen A, Kaarniranta K. AMP-activated protein kinase (AMPK) controls the aging process via an integrated signaling network. Ageing Res Rev. 2012 Apr;11(2):230-41. doi: 10.1016/j.arr.2011.12.005. Epub 2011 Dec 15. PMID: 22186033.
 Federico Pietrocola, Yohann Demont, Francesca Castoldi, David Enot, Sylvère Durand, Michaela Semeraro, Elisa Elena Baracco, Jonathan Pol, Jose Manuel Bravo-San Pedro, Chloé Bordenave, Sarah Levesque, Juliette Humeau, Alexis Chery, Didier Métivier, Frank Madeo, M. Chiara Maiuri & Guido Kroemer (2017) Metabolic effects of fasting on human and mouse blood in vivo, Autophagy, 13:3, 567-578, DOI: 10.1080/15548627.2016.1271513
 Salminen A, Hyttinen JM, Kaarniranta K. AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan. J Mol Med (Berl). 2011 Jul;89(7):667-76. doi: 10.1007/s00109-011-0748-0. Epub 2011 Mar 23. PMID: 21431325; PMCID: PMC3111671.
 Vachharajani VT, Liu T, Wang X, Hoth JJ, Yoza BK, McCall CE. Sirtuins Link Inflammation and Metabolism. J Immunol Res. 2016;2016:8167273. doi: 10.1155/2016/8167273. Epub 2016 Jan 20. PMID: 26904696; PMCID: PMC4745579.
 Kjøbsted R, Hingst JR, Fentz J, Foretz M, Sanz MN, Pehmøller C, Shum M, Marette A, Mounier R, Treebak JT, Wojtaszewski JFP, Viollet B, Lantier L. AMPK in skeletal muscle function and metabolism. FASEB J. 2018 Apr;32(4):1741-1777. doi: 10.1096/fj.201700442R. Epub 2018 Jan 5. PMID: 29242278; PMCID: PMC5945561.
 Jensen J, O'Rahilly S. AMPK is required for exercise to enhance insulin sensitivity in skeletal muscles. Mol Metab. 2017 Feb 1;6(4):315-316. doi: 10.1016/j.molmet.2017.01.012. PMID: 28377870; PMCID: PMC5369262.
 Lin CH, Cheng YC, Nicol CJ, Lin KH, Yen CH, Chiang MC. Activation of AMPK is neuroprotective in the oxidative stress by advanced glycosylation end products in human neural stem cells. Exp Cell Res. 2017 Oct 15;359(2):367-373. doi: 10.1016/j.yexcr.2017.08.019. Epub 2017 Aug 15. PMID: 28821394.
 John E. Gerich, Insulin Resistance Is Not Necessarily an Essential Component of Type 2 Diabetes, The Journal of Clinical Endocrinology & Metabolism, Volume 85, Issue 6, 1 June 2000, Pages 2113–2115, https://doi.org/10.1210/jcem.85.6.6646